Intern, Downstream Process Development
Description
The Intern, Downstream Process Development will support the development and optimization of a platform process enabling ultra‑high‑concentration biologics formulation using Single Pass Tangential Flow Filtration (SP‑TFF) and downstream filtration strategies. The intern will evaluate membrane configurations, operating parameters, and filtration approaches to enable efficient and scalable concentration of monoclonal antibodies and other biologics while maintaining clarity, stability, and product quality. This project will result in a well‑characterized, reproducible process platform that accelerates high‑concentration formulation development for early‑stage biologics programs.
We are thrilled to provide a 10-week paid internship at our facility in Tustin, CA. As an intern, you will dive deep into our team's culture, take on significant projects, and play a vital role in our team's dynamics. This temporary, 40-hour per week office position is designed to offer you a wealth of experience and the chance to connect with professionals in the industry.
Key Responsibilities:
- Assist in designing and executing SP‑TFF and filtration experiments to support ultra‑high‑concentration biologics formulation.
- Evaluate membrane types, module configurations, and operating conditions to optimize flux, yield, throughput, and product quality.
- Perform data collection, analysis, and interpretation of filtration performance, turbidity, stability, and concentration profiles.
- Support development of a platform filtration process by comparing strategies across clarity, manufacturability, scalability, and robustness metrics.
- Document experimental procedures, results, and observations in accordance with development standards.
- Create process summaries, reports, and data presentations for PD stakeholders.
- Collaborate with scientists and engineers in Process Development to understand formulation requirements and process constraints.
- Assist with general lab activities, equipment setup, and method execution as needed.
- Currently pursuing a degree in Biotechnology, Biology, Biochemistry, Chemical Engineering, Bioengineering, or related fields.
- Foundational understanding of biologics processing, filtration principles, or protein chemistry (coursework acceptable).
- Ability to work with laboratory equipment and follow experimental protocols.
- Proficiency with Microsoft Excel for data analysis; familiarity with statistical or plotting tools is a plus.
- Strong analytical and problem‑solving skills with attention to detail.
- Ability to interpret experimental results and communicate findings clearly.
- Solid organizational skills with the ability to manage multiple tasks and timelines.
- Clear written and verbal communication skills.
- Availability to work full-time for the duration of the internship at our Tustin, CA facility.
- Authorization to work in the country where the internship is located.
- Passionate about a career in the biotech industry and looking to gain valuable experience through this internship.
Position Type/Expected Hours of Work:
This role is a temporary position operating Monday through Friday, 5x8 (5 days x 8 hours) schedule.
Internship to begin on Monday, June 15th and end on Friday, August 21st.
What to Expect as an Avid Bio Intern:
- Summer Project: Personalized project plan, complete with a pre-determined roadmap and week by week milestones that the intern will need to meet, ensuring clear expectations and measurable outcomes.
- Mentorship: Your manager and team will provide training, mentorship, and development opportunities.
- Weekly Check-ins and 1:1s: Conduct both on a weekly basis to ensure clear communication and support for our interns.
- Performance Assessments: Conduct mid and end of program performance assessments to be provided with constructive criticism and feedback to help you grow and succeed.
- State of the Art Facility: You will be working amongst the brightest minds in our world class facilities
- Internship Experiences: Intern Open House, Summer Leadership Series, Lunch & Learns, Site Tours, End of Program Presentation
Compensation:
The compensation for this role is $20.00 per hour.
Who you are:
- You have a "bring it on!" team player approach and an unshakable positive attitude, always ready to tackle anything that comes your way.
- Your written and verbal skills are out of this world, and you communicate with clarity and confidence.
- You have exceptional multitasking skills and an unparalleled attention to detail that ensures the smooth running of everything.
- You are a master at building relationships, capable of establishing connections with anyone, be it team members, clients, vendors, or suppliers.
Physical Demands & Work Environment:
In this dynamic role, expect a blend of regular activities like sitting, standing, and walking, with occasional physically engaging tasks such as lifting objects up to 20 pounds. The work environment might expose you to electrical shocks, toxic chemicals, vibrations, or loud noise levels occasionally. However, reasonable accommodations are available to enable individuals with different abilities to perform effectively, ensuring a supportive and adaptable work setting. Your visual acuity, including close, distance, and color vision, will be essential in navigating through the diverse day-to-day demands of this position.