Intern, Translational Biology
BioMarin is the world leader in delivering therapeutics that provide meaningful advances to patients who live with serious and life-threatening rare genetic diseases. We target diseases that lack effective therapies and affect relatively small numbers of patients, many of whom are children. These conditions are often inherited, difficult to diagnose, progressively debilitating and have few, if any, treatment options. BioMarin will continue to focus on advancing therapies that are the first or best of their kind.
BioMarin’s Research & Development group is responsible for everything from research and discovery to post-market clinical development. Research & Development involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class and best-in-class therapeutics that provide meaningful advances to patients who live with rare diseases. Come join our team and make a meaningful impact on patients’ lives.
The mission of Translational Biology is to conduct preclinical translational research evaluating potential therapeutics for severe rare diseases with unmet medical needs. We help provide proof-of-concept preclinical data in relevant disease models and data for understanding of mechanisms of action for these potential therapeutics.
Intern Project Description:
Research summer intern will work on 1 major project and 1 minor project over the 3-month internship. The successful candidate will partner closely with a team of scientists from translation biology, and other functional groups within BioMarin. He/She will primarily be responsible for executing in vitro, and ex vivostudies to assess pharmacokinetics, efficacy and mechanism of action of potential therapeutics.
The responsibilities of the candidate are to:
- Maintain and expand cell culture
- Make protein lysates and DNA and RNA from cells and tissues
- Determine target expression by varies methods, including but not limited to flow cytometry, quantitative PCR or western blot
- Notebook keeping, compilation of data and interpretation into power point presentations
- The intern will be working on one of two diverse projects (to be determined):
Applicants should be at least in their 3rdor 4thyear obtaining a BA/BS in Biochemistry, Molecular Biology, or Genetics. MS are also encouraged to apply. Strong performance in relevant academic courses in is required. Candidates with previous laboratory experience in protein/DNA/RNA purification, PCR, westerns, and/or cell biologywill be preferred. The position requires self-motivation, teamwork, and dedication to quality in a fast-paced scientific setting.
We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.