Medical Director

Clinical Development Seattle, Washington


Why Work for Us?

Innovation  Act with Integrity. Collaboration. Embrace Diversity. Care

We come from many countries, cultures, races, ethnicities, abilities and nationalities. We bring our passions including singing, biking, swimming, dancing, cooking, volunteering, parenting, coaching and much more! We are proud of our nearly equal balance of men and women and strengthened by our non-binary and transgender team members. Every employee belongs.

We offer challenging career opportunities, competitive benefits and an environment that recognizes and rewards performance. 

Company Description

Zymeworks is a clinical-stage biopharmaceutical company dedicated to the discovery, development and commercialization of next-generation bispecific and multifunctional biotherapeutics, initially focused on the treatment of cancer.  Zymeworks’ suite of complementary therapeutic platforms and its fully-integrated drug development engine provide the flexibility and compatibility to precisely engineer and develop highly-differentiated product candidates.

Zymeworks is seeking a highly-motivated professional who is looking to grow their career with our company.

This position will report to the Executive or Senior Medical Director and will be based in Vancouver, BC or Seattle, WA.

Key Responsibilities

  • Provide medical/scientific, strategic and operational expertise and support for the planning and execution of IND filings, Phase I trials, Phase II and later stage trials.
  • Provide expert opinion on the pathophysiology, diagnosis, existing and emerging treatment options and unmet medical needs to inform key medical and business decisions. 
  • Conduct medical monitoring of clinical development programs; writes protocols, investigator brochures, informed consent documents; responses to questions from regulatory agencies, institutional review boards and ethics committees and study reports; reviews clinical data, case report forms and ensures final accuracy of clinical trial data.
  • Conduct safety monitoring, oversee conduct of clinical sites for adherence to both company standards, and government/industry regulations (GCP/ICH), standard of care evaluation; trains investigators and travel to clinical sites to build relationships with investigators and study teams in support of study enrollment.
  • Institute and continuously improve operating procedures ensuring best practices.
  • Establish appropriate strategic partnerships with centers of excellence, advocacy groups and KOLs in the areas of scientific interest.
  • Collaborate closely with key stakeholders to ensure tight strategic integration of product development plans and strategies. Plans and develops content for advisory meetings with opinion leaders and medical symposia.
  • Participate in review of promotional and medical materials to ensure content is medically appropriate and compliant with internal and external requirements.
  • Keep up to date on current relevant therapeutic areas through familiarity with literature, attendance at meetings, conventions, and professional associations.

Qualifications and Experience 

MD or equivalent degree (eg. DO or MBBS) with experience in clinical oncology. A minimum of 0-2 years of progressive experience in the biotech or pharmaceutical industry, or equivalent combination of post-fellowship training experience. 

Skills and Abilities

  • Proven interpersonal skills with the ability to work collaboratively as a member of a cross-functional team.
  • Ability to establish and maintain effective working relationships.
  • Strong leadership skills and the ability to lead through example. 
  • Experience in or knowledge about drug-development procedures. Industry/academic experience in planning, executing, and reporting clinical trials is preferred.
  • Strong understanding of clinical trials process with demonstrated ability to have designed and implemented programs and initiatives directed towards defined strategic objectives.
  • Early-stage development and regulatory experience preferable.
  • Excellent organizational skills and the ability to manage concurrent deliverables and work effectively in a challenging, milestone-driven environment.
  • Strong problem-solving skills and the ability to think and act strategically, anticipate roadblocks and map out next steps.
  • Demonstrated high level of integrity, ethics, and professionalism.
  • Knowledge of scientific methods, research design and medical practices and procedures.
  • Excellent written, oral and presentation skills. Demonstrated ability to communicate scientific results.
  • Ability to travel.
  • An equivalent combination of education and experience may be considered.
  • Embody and champion Zymeworks’ values: Act with Integrity. Collaborate. Care.
  • Adhere to the highest degree of professional standards and strict confidentiality on matters that require discretion.
  • Lead and develop team of clinical professionals.

How to Apply

If you are interested in this challenging opportunity, please apply online at Due to the high volume of applicants, only those selected for interviews will be contacted.

NOTE TO EMPLOYMENT AGENCIES: Zymeworks values our relationships with our Recruitment Partners. We will only accept resumes from those partners whom have been contracted by a member of our Human Resources team to collaborate with us. Zymeworks is not responsible for any fees related to resumes that are unsolicited or are received without contract.