Senior Scientist, Analytical Development
Description
Sutro has a unique capability that enables new molecular entities to be designed using a hybrid of synthetic and recombinant technologies to create best in class therapeutics in the oncology and auto-immune disease space. Our portfolio includes antibody-drug conjugates, bispecific antibodies, cytokine derivatives and other novel immuno-stimulatory approaches.
Sutro Biopharma, Inc. is looking for a Scientist to join our Analytical Development group to support mass spectrometry and chromatography assay development for monoclonal antibodies, bispecific antibodies, cytokines, and antibody drug conjugates.
Responsibilities:
• Develop new chromatography assays for characterization of recombinant proteins and conjugates.
• Perform testing to support upstream/downstream development, formulation development and manufacturing.
• Qualify assays, support technology transfer to Sutro QC and contract testing laboratories.
• Author and review SOPs, protocols and technical reports.
• Work collaboratively within Analytical Development, other functional areas, external partners and CMOs.
• Perform routine maintenance and troubleshoot mass spectrometers and HPLCs
• May direct multidisciplinary project teams, or perform as project lead
• Cross functional interactions with senior leaders in contributing and executing goals
• Presents data to senior managers and peers as a recognized leader in their field
Qualifications:
• PhD in analytical chemistry, biochemistry, molecular biology or related scientific field and 7+ years of industry experience in the characterization of large molecule biologics is required OR
• BS/MS in analytical chemistry, biochemistry, molecular biology or related scientific field and 15+ years of industry experience in the characterization of large molecule biologics is required.
• Thorough understanding of protein separation methods combined with the experience in developing assays is essential. Qualifying and transferring assays to QC environment is desired.
• Expertise in operation and maintenance of HPLCs is highly preferred.
• Knowledge of additional analytical assays such as icIEF, capillary electrophoresis and activity assays is desirable.
• Experience with automated liquid handlers is desirable.
• Demonstrated leadership ability, including a commitment to mentorship and development of personnel.
• Flexibility to work on multiple projects in a fast-paced environment is essential.
• Good communication skills are essential.
• Demonstrated track record of execution and collaboration, with a focus on analytical methods using chromatography or other separation techniques
• Demonstrated track record of execution and collaboration, with a focus on analytical methods using chromatography or other separation techniques
Sound exciting? Apply today and join our team!
Sutro Biopharma, Inc. encourages all colleagues to be fully vaccinated for COVID-19 prior to the first date of employment.
As an equal-opportunity employer, we believe in fostering a culture that is inclusive and values diversity in background and opinions. Sutro Biopharma hires extraordinary individuals into every position in the company and is committed to the diversity of our team. Our company progresses without regard to race, ethnicity, gender, sexual orientation, religious belief, age, disability or citizenship status. We are dedicated to creating a safe environment where our employees can grow and succeed together.
We look forward to hearing from candidates who are interested in exploring opportunities with Sutro! Our People & Culture team/hiring managers are unable to respond and do not accept solicitations from third-party agencies.
The anticipated salary range for fully qualified candidates applying for this role at Sutro Biopharma’s California-based locations will be $162,000 - $189,000 (not including bonus, equity, and benefits). The final salary offered will be dependent on several factors that include and are not limited to relevant previous experience, job responsibilities and duration of experience, the type and length of experience within the industry, and education.
About Sutro Biopharma
Sutro Biopharma, Inc., is a clinical-stage company relentlessly focused on the discovery and development of precisely designed cancer therapeutics, transforming what science can do for patients. Sutro’s fit-for-purpose technology, including cell-free XpressCF®, provides the opportunity for broader patient benefit and an improved patient experience. Sutro has multiple clinical stage candidates, including luveltamab tazevibulin, or luvelta, a registrational-stage folate receptor alpha (FRα)-targeting ADC in clinical studies. A robust pipeline, coupled with high-value collaborations and industry partnerships, validates our continuous product innovation. Sutro is headquartered in South San Francisco. For more information, follow Sutro on social media @Sutrobio, or visit www.sutrobio.com.