Research Scientist IND to Medicine

Research Bothell, United States


Position at Seagen

Seagen is a global, multi-product biotechnology company dedicated to developing and commercializing transformative cancer medicines. As the industry leader in antibody-drug conjugate (ADC) technology, we pioneered a new generation in the science of harnessing antibodies to deliver cell-killing agents directly to cancer cells. Seagen’s dedication to improving the lives of cancer patients goes beyond science, and we believe that every employee has a role in contributing to this mission. By working together with a shared dedication and diverse perspectives, we are able to reach our full potential and make a real difference in the world. Seagen is a fast-growing company and has an abundance of opportunities available for you to grow your career. Put your passion to work at Seagen and join us! 


Seagen is seeking a highly collaborative Research Scientist to lead research activities supporting drug development candidates and early-stage investigational clinical agents. This individual is expected to contribute to the team goals by performing laboratory work and, depending on the experience, serve as Research Lead on cross-functional project teams focused on biologic therapeutics for oncology. They should be able to quickly pivot among projects as needed, and have a record of being a strong scientist, team player, strategic thinker, and an effective communicator.  

Principal responsibilities: 

  • Develops and implements research plans aimed at expanding our understanding of therapeutic MOAs, predictors of sensitivity and resistance, and combination strategies as they emerge and evolve 
  • Identifies critical path experiments aligned with research and development project team goals. 
  • Prioritizes resources in alignment with the research leadership team 
  • Work independently and demonstrate the ability to contribute to projects outside their expertise 
  • Serves as a single research point of contact for cross-functional/interdepartmental research activities that support regulatory filings and expanded clinical opportunities 
  • Ensure pharmacology studies are appropriately documented and summarized 
  • Collaborate with clinical and translational sciences to help guide the clinical development strategy for novel therapeutic 
  • May provide research support/oversight for external collaborations 
  • Communicate learnings from translational and clinical studies to the therapeutic design research group to maximize the potential of pre-clinical molecules 
  • May provide research support/oversight for external collaborations and/or MTAs and represent research on advisory boards. Presents research at scientific conferences, key contributor to regulatory documents and peer-reviewed publications 

Required Qualifications 

  • Ph.D. degree in Biology, Biochemistry, Bioengineering, Immunology, or another related field 
  • Candidates with a BS or MS degree but extensive drug development experience in a biotech industry setting will also be considered 

Preferred Qualifications: 

  • 2-3 years of postdoctoral experience in oncology preclinical and translational research or in the biotech industry 
  • Knowledge and expertise in oncology drug development, therapeutic antibodies, and/or ADCs. 
  • Experience with in-vitro hematological and solid tumor cell lines and primary samples 
  • Strong background in experimental cancer biology, biochemical and/or immunological techniques (e.g. multiparametric flow cytometry, Elisa, Western blot, lentiviral delivery, immunofluorescence) 
  • Broad knowledge of cancer cell signaling and genetics 
  • Proven proficiency in the design of in vivo experiments as well as sample assessment using a variety of laboratory techniques 
  • Strong written and verbal communication skills with the ability to communicate effectively to a wide range of audiences 
  • Experience working in cross-functional matrix teams 
  • Demonstrated record of publications in high-quality scientific journals and/or presentations at scientific conferences 


As the leading employer in our industry in the Pacific Northwest, Seagen is proud to offer a competitive total compensation package as well as a comprehensive benefits program designed to support the whole lives of our employees and their families. Benefits include medical, vision and dental coverage, group and supplemental life insurance, 401(k) with company match, tuition reimbursement, relocation assistance and much more. To learn more about Seagen, please visit  

Seagen is an equal opportunity employer. All qualified applications will receive consideration for employment without regard to race, age, gender identity, sexual orientation, color, religion, sex, marital status, national origin, protected veteran status, disability status, or any other status protected by federal, state, or local law.  

To prevent the spread of COVID-19, and as an integral part of its public health and safety measures, Seagen requires that all newly-hired employees be fully vaccinated against COVID-19 before commencing employment, subject to reasonable accommodation and other requirements of applicable federal, state, and local law.