Research Scientist Late-Stage Programs

Research Bothell, United States


Description

Position at Seagen

Seagen is a global, multi-product biotechnology company dedicated to developing and commercializing transformative cancer medicines. As the industry leader in antibody-drug conjugate (ADC) technology, we pioneered a new generation in the science of harnessing antibodies to deliver cell-killing agents directly to cancer cells. Seagen’s dedication to improving the lives of cancer patients goes beyond science, and we believe that every employee has a role in contributing to this mission. By working together with a shared dedication and diverse perspectives, we are able to reach our full potential and make a real difference in the world. Seagen is a fast-growing company and has an abundance of opportunities available for you to grow your career. Put your passion to work at Seagen and join us! 

Summary:

Seagen is seeking a highly collaborative Scientist to lead research activities supporting therapeutic agents in clinical stage of development. This individual will be responsible for research activities on cross-functional project teams for drug development candidates, and/or approved therapeutics. The successful candidate will contribute to Clinical Stage Product Teams by supporting Research Leads. They should have a sustained record of being a strong scientist, team player, strategic thinker, and an effective communicator.

Principal Responsibilities: 

  • Develops and implements research plans aimed at expanding our understanding of therapeutic mechanisms of action, predictors of sensitivity and resistance, combination strategies, and expansion of patient populations as they emerge and evolve. 
  • Collaborates with clinical and translational sciences to help guide the clinical development strategy for novel therapeutics. 
  • Contributes to cross-functional/interdepartmental research activities that support regulatory filings and expanded clinical opportunities 
  • Identifies and prioritizes critical path experiments aligned with research and development project team goals. 
  • Designs and executes cell-based assays and ensures in vivo pharmacology studies are appropriately documented. 
  • Communicates learnings from translational and clinical studies to therapeutic design research group to maximize the potential of pre-clinical molecules.   
  • May provide research support/oversight for external collaborations and/or MTAs. 
  • Presents research at scientific conferences and is a key contributor to regulatory documents, patent applications, and peer-reviewed publications. 

Required Qualifications: 

  • PhD in Cancer Biology, Cell Biology, Immunology, Biochemistry, Bioengineering, or relevant field; or BS (7+ years)/MS (5+ years) in related field with directly relevant industry experience in drug discovery and/or development.  
  • Strong knowledge and expertise of oncology, cell biology, and drug development. 
  • Demonstrated record of first-author publication(s) and/or presentation(s) at scientific conferences. 
  • Experience leading or contributing core technical expertise to project teams. 

Preferred Qualifications: 

  • Experience leading and/or supporting research in therapeutic drug development 
  • Demonstrated ability to independently identify, plan, and manage critical path experiments in alignment with team objectives, across multiple projects. 
  • Ability to use critical thinking to solve complex problems, address challenges, overcome obstacles, and plan for the future. 
  • Highly effective interpersonal skills, ability to identify and absorb critical information and convey it to relevant stakeholders. 
  • Strong written and verbal communication skills with the ability to communicate effectively to a wide range of audiences. 
  • Strong collaborator with ability to function across teams and a variety of disciplines. 
  • Ability to gain support and commitment for research plans using compelling rationale. 
  • Ability to recognize and deliver on key department and project objectives. 
  • Ability to adapt and adjust to a rapidly evolving environment. 
  • Strong management and mentoring skills. 

  

In addition to the above, a base of scientific knowledge and experience that encompasses a subset of the following areas: 

  • Knowledge of small molecules, therapeutic antibodies, and/or ADCs 
  • Knowledge of signal transduction and/or metastasis pathways 
  • Expertise in biochemical techniques, imaging, and/or cell-based assay development 
  • Expertise in lentiviral systems and/or cell line engineering 
  • Expertise in protein expression analysis through orthogonal approaches 
  • Expertise in mouse models, including xenografts and/or orthotopic models 
  • Experience with utilization and analysis of data from ‘omics platforms 

As the leading employer in our industry in the Pacific Northwest, Seagen is proud to offer a competitive total compensation package as well as a comprehensive benefits program designed to support the whole lives of our employees and their families. Benefits include medical, vision and dental coverage, group and supplemental life insurance, 401(k) with company match, tuition reimbursement, relocation assistance and much more. To learn more about Seagen, please visit www.seagen.com.  

Seagen is an equal opportunity employer. All qualified applications will receive consideration for employment without regard to race, age, gender identity, sexual orientation, color, religion, sex, marital status, national origin, protected veteran status, disability status, or any other status protected by federal, state, or local law.  

To prevent the spread of COVID-19, and as an integral part of its public health and safety measures, Seagen requires that all newly-hired employees be fully vaccinated against COVID-19 before commencing employment, subject to reasonable accommodation and other requirements of applicable federal, state, and local law. 

#LI-KO1