Scientist BioProcess Development, Cell Culture

Process Sciences Bothell, Washington



The Cell Culture group within the BioProcess Development department is seeking a highly motivated Scientist to participate in the cell culture process and technology developments. Cell Culture plays a key role in the product supply chain through developing the upstream portion of the manufacturing processes for clinical and commercial antibodies. The Scientist will be responsible for supporting all stages of CMC programs, and working in collaboration with internal and external stakeholders. Additionally, this person will contribute to continuous process improvement by characterizing the equipment and elucidating the engineering aspects of the processes to ensure that the group is on the cutting edge of the upstream process development in the advancement of cancer therapies.

Principal Responsibilities:

  • Work as a member of the Cell Culture group and to support and achieve group, departmental, and company goals
  • Execute CMC activities related to cell culture process development including support the establishment of clonal cell line, phase-appropriate process development and characterization, technology transfer to GMP manufacturing and drafting of regulatory submissions
  • Apply engineering principles and participate in technology advancement projects to improve cell culture platform process as well as to enhance process-to-product understanding
  • Accurately and thoroughly document laboratory work in electronic notebooks and subsequent technical reports

 Required Qualifications:

  • PhD in Chemical Engineering, Biochemical Engineering, Biomedical Engineering, Bioengineering or related fields with relevant post-doctoral experience. Bachelor/Master's degree in same fields will be considered with additional, relevant work experience
  • Proficiency with standard mammalian cell culture techniques (e.g. aseptic technique, passaging cells, preparing cell culture media, etc.)
  • Apply scientific and technical experience in initiating new projects or bringing new scientific technologies that address important business needs
  • Ability to collaborate and work effectively on cross-functional teams, and rapidly adapt technologies and processes to meet the needs of growing pipeline
  • Excellent verbal and written communication skills to author reports, regulatory submissions, and publications
  • Ability to adapt to changing timeline and priorities

 Preferred Qualifications:

  • Proficient with stirred-tank bioreactor, and use it to develop, optimize, characterize and scale-up mammalian cell culture process to support CMC programs
  • Familiar with fed-batch and/or perfusion cell culture processes
  • Relevant biotechnology industry and GMP manufacturing experience or knowledge

As the leading employer in our industry in the Pacific Northwest, Seattle Genetics is proud to offer a competitive total compensation package as well as a comprehensive benefits program designed to support the whole lives of our employees and their families. Benefits include medical, vision and dental coverage, group and supplemental life insurance, 401(k) with company match, tuition reimbursement, relocation assistance and much more. To learn more about Seattle Genetics, please visit

Seattle Genetics is an equal opportunity employer. All qualified applications will receive consideration for employment without regard to race, age, gender identity, sexual orientation, color, religion, sex, marital status, national origin, protected veteran status, disability status, or any other status protected by federal, state, or local law.