Principal Pathologist

Translational Sciences Bothell, Washington



To meet the expanding needs of our company, Seagen is seeking an anatomic pathologist with exceptional scientific curiosity, critical thinking, and self-motivation to join our growing team within Translational Sciences.  The position will focus on Discovery Pathology and support our strong early pipeline as we search for innovative new cancer therapeutics.  You will be an integral driver for translating discovery research into the clinic, including target validation, target liability assessment, investigative toxicology, early lead screening, biomarker discovery, and development.  Our company culture places a premium on scientific excellence, innovation, and teamwork.  You will contribute expertise to a highly skilled multidisciplinary team dedicated to helping cancer patients using both traditional and state-of-the-art pathology techniques, such as digital image analysis, multi-spectral imaging, or multiplex immunofluorescence.  This team approach requires excellent interpersonal skills, clear communication, accountability, and self-motivation.  To be successful in this science-based role, you must have exceptional critical thinking and problem-solving abilities.  The compensation package is flexible and will be determined based on the qualifications and experience level of the candidate. 


  • Provide pathology expertise to facilitate target identification/validation, biomarker discovery/development, investigation of toxicities, and pharmacology discovery research 
  • Design and conduct studies to investigate mechanisms of action of Seagen therapeutics and platforms 
  • Interpret and report pathology endpoints to progress therapeutics through the pipeline from discovery to launch 
  • Foster continued development of the group’s pathology expertise through primary data generation or peer review of internal and external studies 
  • Assist in identifying, evaluating, and implementing new technologies or techniques in our in-house pathology laboratories 
  • Provide internal expertise to understand the mechanisms of toxicity observed non-clinically and/or clinically in order to drive mitigation and/or back-up strategies to minimize potential harm to patients 
  • Present data and interpretations in written and oral form 
  • Build collaborative networks both internal and external to the company to ensure rapid communication and cross-functional evaluations and investigation 
  • Develop strong knowledge of the basic biology of Seagen targets and platforms and contribute to the development of the next generation of cancer therapeutics 
  • Represent Seagen in the external scientific community 


  • 3-5 years of pathology experience in an academic or pharmaceutical/biotech setting 
  • Demonstrated skills in critical thinking, problem solving, and mechanistic investigation evidenced by scientific publications or presentations   
  • Understanding of and experience with basic and advanced tissue-based investigative techniques such as immunohistochemistry, in situ hybridization, immunofluorescence, digital image analysis, electron or confocal microscopy, laser capture microdissection, etc. 
  • Experience applying research techniques to drug discovery and development 

Education and Certification: 

  • D.V.M. (or equivalent) 
  • Ph.D. in toxicology, pathology, comparative biology, or a related field 
  • Diplomate, American College of Veterinary Pathologists (or equivalent) in anatomic pathology 

As the leading employer in our industry in the Pacific Northwest, Seagen is proud to offer a competitive total compensation package as well as a comprehensive benefits program designed to support the whole lives of our employees and their families. Benefits include medical, vision and dental coverage, group and supplemental life insurance, 401(k) with company match, tuition reimbursement, relocation assistance and much more. To learn more about Seagen, please visit  

Seagen is an equal opportunity employer. All qualified applications will receive consideration for employment without regard to race, age, gender identity, sexual orientation, color, religion, sex, marital status, national origin, protected veteran status, disability status, or any other status protected by federal, state, or local law.