Principal Scientist Formulation

Technical Operations & Process Sciences Bothell, United States


Description

Position at Seagen

Summary:

A successful Senior/Principal Scientist & Technical Development Lead will enhance the long-term growth of Seagen’s development organization through innovation, collaboration, and scientific excellence, increasing our internal capabilities and improving operational efficiency to deliver transformative cancer therapies. This specific role is scoped to include leadership of technical development activities for a late-stage clinical asset at Seagen.

Requirements or Responsibilities:

  • Lead technical development sub-team for early- and late-stage programs to define and execute CMC strategy
  • Lead the development of robust liquid and lyophilized products for antibodies and antibody-drug conjugates (ADCs)
  • Leverage literature, global regulatory guidance, and practical experience to complete deliverables and influence CMC strategies
  • Recommend and implement new technology that advances knowledge and productivity within the department
  • Identify and lead initiatives to increase capabilities, enhance process efficiency, or improve cross-functional operations
  • Motivate and support the career development and technical growth of direct reports
  • Author and review technical reports, manufacturing documents, and global regulatory submissions
  • Present internally at department, project team, and governance, and externally at scientific conferences, industry groups, and workshops

Qualifications:

  • 2+ years supervisory
  • 5+ years of experience leading matrixed teams
  • Hands-on experience and excellent understanding of analytical and biophysical protein characterization
  • Excellent oral and written communication skills, ability to lead cross-functional development teams, and capability to provide strategic contributions
  • Principal Scientist level requires broad subject matter expertise in multiple technical areas of formulation or DP process development and a working knowledge of both
  • Demonstrated experience supporting regulatory submissions and a thorough understanding of ICH and global regulatory guidance

Education:

  • S. or Ph.D. in Pharmaceutical Sciences, Biological Sciences, Biomedical or Chemical Engineering, Material Science, or a related discipline
  • Principal Scientist level – Ph.D. with 5+ years of industry experience; M.S. with commensurate amount of industry experience
  • Senior Scientist level – Ph.D. with 3+ years of industry experience; M.S. with commensurate amount of industry experience


#LI-KP1