Invivo Xenograft Specialist - Senior Research Associate

Translational Sciences Bothell, Washington



Seagen is seeking a highly motivated, innovative, and technically-skilled senior Research Associate to advance our efforts to evaluate efficacy of novel oncology therapeutics and develop rodent disease models.   Our company culture places a premium on scientific excellence, innovation, and teamwork to develop translational models that have meaningful impact in the development of biopharmaceuticals and treatment of cancer. We place a strong emphasis on thoughtful, data-driven study design and strive to maximize actionable data acquired from each experiment. The successful candidate will become an integral member of the Comparative Biology team within Nonclinical Sciences and contribute independently to projects with the goal of identifying the most effective drugs to advance from early discovery to clinical drug development.   


Principal Responsibilities:

  • Independently plan, coordinate, execute, and analyze results of complex pharmacology studies in rodent oncology models
  • Understand project strategy, drive key components forward, and propose new experiments or methods to further advance the project
  • Advise and consult with research staff across multiple groups on the optimal study design and technical procedures to meet project goals
  • Interact with colleagues in the Comparative Biology team and in cross-functional teams to coordinate intra-group and inter-group study planning and execution
  • Implement novel animal models to address research questions
  • Design and conduct in vitro and ex-vivo experiments to understand the mechanism of action of therapeutic candidates
  • Develop/implement operational strategies to standardize workflow and increase throughput
  • Provide regular data updates and present experimental findings at internal and external meetings
  • Author sections of study reports, manuscripts, or posters
  • Maintain meticulous laboratory records, electronic files, and laboratory notebooks to support experimental studies


Required Qualifications:

  • Minimum of 5+ years (B.S.) or 3+ years (MS) technical working with rodent models in a biology/biomedical (or similar) research laboratory
  • High level of expertise in mouse and rat procedures including tumor implantation, tumor growth monitoring, dosing (IP, IV, PO, SC, etc), aseptic surgery, and blood and tissue collection, handling and processing
  • Experience with mammalian cell culture establishment, expansion, and characterization
  • Solid understanding of concepts and principles of molecular, cellular, cancer, and immune biology
  • Familiarity with database software (e.g., Access), data analysis programs (e.g., Excel, Prism, or Spotfire), and presentation tools (e.g., PowerPoint)
  • Ability to troubleshoot, interpret, and summarize scientific data in an accurate, critical, and concise manner
  • Excellent verbal and written communication skills and a demonstrated ability to work cross-functionally and collaboratively
  • Excellent organization and ability to handle multiple tasks and prioritize


Preferred Qualifications:

  • Experience with implementing advanced, clinically-relevant, rodent oncology models
  • Working knowledge in the function of the immune system and experience in experimental models of antitumor immunity


As the leading employer in our industry in the Pacific Northwest, Seagen is proud to offer a competitive total compensation package as well as a comprehensive benefits program designed to support the whole lives of our employees and their families. Benefits include medical, vision and dental coverage, group and supplemental life insurance, 401(k) with company match, tuition reimbursement, relocation assistance and much more. To learn more about Seagen, please visit 

Seagen is an equal opportunity employer. All qualified applications will receive consideration for employment without regard to race, age, gender identity, sexual orientation, color, religion, sex, marital status, national origin, protected veteran status, disability status, or any other status protected by federal, state, or local law.