Director Laboratory Automation System Infrastructure & Informatics

Research Bothell, United States


Description

Position at Seagen

Seagen is a global, multi-product biotechnology company dedicated to developing and commercializing transformative cancer medicines. As the industry leader in antibody-drug conjugate (ADC) technology, we pioneered a new generation in the science of harnessing antibodies to deliver cell-killing agents directly to cancer cells. Seagen’s dedication to improving the lives of cancer patients goes beyond science, and we believe that every employee has a role in contributing to this mission. By working together with a shared dedication and diverse perspectives, we are able to reach our full potential and make a real difference in the world. Seagen is a fast-growing company and has an abundance of opportunities available for you to grow your career. Put your passion to work at Seagen and join us! 

 

Summary: 

This is an associate director / director level position responsible for expanding the automation capabilities in Research and Translational Sciences laboratories to support drug discovery and development. This newly created role reports into the VP Core Research & Technologies Group and supports Research & Translational Sciences activities including biological, chemical, analytical and platform processes. The successful candidate will lead the efforts to realize a future state where automation, high throughput workflows, process optimization, and informatics are maximally leveraged to support and enhance our expanding therapeutic discovery and development pipeline. The candidate will partner with leaders from Research, Translational Sciences, Technical Operations & Process Sciences (TOPS), Data Science, and IT to develop a vision and execution plan for a connected automated laboratory, and consistent with company objectives. In addition, the role will work closely with laboratory staff to enable hands-on support for automation instruments and programming. With success,  the role will be responsible for growing the function and managing staff commensurate with expanded capability and workload. 
 
Principal Responsibilities: 

  • Develop strategy and execution plan for a connected and automated laboratory to support development functions across Research & Translational Sciences and peers with the mission of development and delivery of efficient automated processes to enable Research portfolio progression 
  • Maximize use of laboratory automation to reduce human error and to increase lab efficiency and productivity 
  • Serve as strategic lead for laboratory robotics within Research and across peer groups 
  • Build a community of practice with aligned strategy and approach toward lab automation; develop and sustain best practices for laboratory automation systems 
  • Work with functional area leaders to assess and implement end-to-end high throughput process development including data flow  
  • Collaborate with Data Science and IT to structure data in a FAIR manner and automate data flow between instrument, robots, ELN, data warehouse, and analyses 
  • Interface with Research and Translational Science staff to support all aspects of laboratory automation implementation including ideation, planning, procurement, method development and instrument qualification, user training, and on-going support. Examples include: 
  • Serve as “help desk” to support automation equipment and efforts as issues/needs arise 
  • Help evaluate and determine appropriate automation technology  
  • Perform minor repair work on automated systems (Tecan, Hamilton, AMBR, etc.)  
  • Provide support for complex instrumentation with many integrated systems, including error handling/troubleshooting efforts  
  • Develop application-specific protocols for complex automated instrumentation, which may require integration with third-party devices 
  • Support programming/script writing  
  • Fine tuning of methods/scripts  
    • Teaching/recalibrating of vector positions  
    • Movement tests, water tests, and error message handling  
    • Optimization of movements and speeds 
    • Optimization of current scripts to improve efficiency  
  • Assist on-boarding of new instrumentation and training of users 
  • May include liquid class definition and optimization 
  • May provide instrument validation support for QC 
  • Contribute to annual Capital Planning and Life-cycle management of Lab Automation platform 
  • Develop an operational budget and resource model to support a 5-year roadmap for the automation function 
  • Recruit talent and grow function per automation roadmap 

Qualifications: 

  • MS. / Ph.D. or equivalent in relevant science and/or engineering discipline  
    •  Associate Director 
      • MS and 10+, or Ph.D. with 8+ years of industrial experience in laboratory automation and data engineering 
      • 4+ years supervisory or leadership experience 
    •  Director 
      • MS and 12+, or Ph.D. with 10+ years of industrial experience in laboratory automation and data engineering 
      • 6 + years of supervisory or leadership experience 
      • Demonstrated leadership in automation/robotics for pharmaceutical/biotechnology laboratories 
      • Demonstrated expertise in advanced programming and controls of commonly used automation instruments such as Tecan and Hamilton 
      • Must stay current on the latest automation technology, tools, best practices, and trends 

As the leading employer in our industry in the Pacific Northwest, Seagen is proud to offer a competitive total compensation package as well as a comprehensive benefits program designed to support the whole lives of our employees and their families. Benefits include medical, vision and dental coverage, group and supplemental life insurance, 401(k) with company match, tuition reimbursement, relocation assistance and much more. To learn more about Seagen, please visit www.seagen.com.  

Seagen is an equal opportunity employer. All qualified applications will receive consideration for employment without regard to race, age, gender identity, sexual orientation, color, religion, sex, marital status, national origin, protected veteran status, disability status, or any other status protected by federal, state, or local law.  

To prevent the spread of COVID-19, and as an integral part of its public health and safety measures, Seagen requires that all newly-hired employees be fully vaccinated against COVID-19 before commencing employment, subject to reasonable accommodation and other requirements of applicable federal, state, and local law. 

 
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