Director, Chief of Staff to CEO

General & Administrative Cambridge, Massachusetts


Company Overview

Repertoire Immune Medicines is a clinical-stage biotechnology company working to unlock and direct the remarkable power of the human immune system to prevent or treat cancer, as well as autoimmune and infectious disease.  The company is founded on the belief that the repertoire of T cell receptor (TCR)-antigen codes that drive health and disease represents one of the greatest opportunities for innovation in medical science.  Repertoire scientists created and developed the DECODE and DEPLOY suite of technologies, which allow in-depth characterization of TCR-antigen pairs, and the ability to rationally design and develop novel targeted immune medicines.

From its sites in Cambridge, Mass., and Zurich, Switzerland, Repertoire’s team of more than 120 is creating a new category of immune medicines enabled from its DECODE discovery platform.  The company’s first product in the clinic is a novel multiclonal T cell therapy consisting of T cells derived from the peripheral blood, activated against a curated set of antigens, and armed with a proprietary cytokine.  Repertoire is in clinical-stage immuno-oncology development today, targeting metastatic solid tumors.  In the field of autoimmunity, Repertoire is using its proprietary platform to discover novel epitopes and TCRs from patients with type 1 diabetes.  The company is also using its DECODE platform to discover infectious disease antigens and responding T cell clones.

Role Overview

The Chief of Staff will report directly to the CEO.  This strategic position focuses on ensuring that the organization is being run smoothly and effectively.  Being effective in this role requires a natural aptitude for building strong, trusting partnerships across the organization.

This position requires a hands-on, self-motivated, smart, and emotionally intelligent individual who thrives in a fast-moving, dynamic environment within a complex and fast-changing industry.  This person anticipates needs and demands and works to provide logical, innovative, and creative solutions without explicit instruction.  S/he will be expected to communicate changes in prioritization and decision-making efficiently and be capable of carrying out multiple projects while effectively prioritizing tasks according to the needs of the CEO and the organization.

Key Responsibilities

  • Partners with the CEO and Executive Committee (EC) to ensure that goals and objectives are being appropriately tracked and achieved, and that priorities are being communicated effectively.
  • Partner with Executive Committee members to ensure milestones are established and communicated relating to key functional projects.
  • Partner with the CEO on the company strategy development process with Executive Committee.
  • Manage the CEO’s staff meeting and senior leadership team’s subcommittee meetings; draft agendas, coordinate presentations, manage attendees, create, and distribute meeting minutes.
  • Partner with the CHRO to facilitate the annual goal setting process and manage the quarterly goal status reviews.
  • In partnership with the executive management team and CEO, develop/coordinate building of PowerPoint decks for Board Meetings, All-Hands meetings, Field Visits; manage the CEO report to the board.
  • Actively enable the efficiency of business operations from behind the scenes.
  • In partnership with the CEO executive admin, oversee extensive travel and meeting schedules for the CEO and office including transportation, accommodations, and speech preparation as well as other such needs as they arise.
  • Compose and manage correspondence dealing with issues or subject matter that is highly sensitive and confidential.


  • Bachelor's degree required; MBA preferred. Minimum of 8 years of experience.
  • Background in operations, administration, or a startup environment within the biologics/pharmaceutical industry is preferred.
  • Exceptional interpersonal skills and ability to partner with multiply functional area leaders.
  • Strong analytical skills and ability.
  • Willingness to work hard and take direction while also anticipating problems and their solutions without explicit guidance.
  • Highly developed verbal and written communication skills with a demonstrated ability to compose correspondence and content materials with a nuanced understanding of industry-specific subject matter, company standards, and procedural guidelines.
  • The ability to work well under tight deadlines and to respond to rapidly changing demands.


Repertoire is committed towards social responsibility and developing an inclusive culture. Much as the power of the immune system lies in the diversity of T and B cells, our work requires the creativity and ingenuity of a diverse workforce.  We believe in actively pursuing equity in all facets of the work experience at Repertoire.  We will continue to educate ourselves about the inequities and barriers present in our society and take action as a company where we can make a difference.

Repertoire is proud to be an Equal Opportunity Employer.