Lab Manager/Sr. Lab Manager

Tech Ops Cambridge, Massachusetts


Company Overview

Repertoire Immune Medicines is a clinical-stage biotechnology company working to unlock and direct the remarkable power of the human immune system to prevent or treat cancer, as well as autoimmune and infectious disease.  The company is founded on the belief that the repertoire of T cell receptor (TCR)-antigen codes that drive health and disease represents one of the greatest opportunities for innovation in medical science.  Repertoire scientists created and developed the DECODE and DEPLOY suite of technologies, which allow in-depth characterization of TCR-antigen pairs, and the ability to rationally design and develop novel targeted immune medicines.

From its sites in Cambridge, Mass., and Zurich, Switzerland, Repertoire’s team of more than 170 is creating a new category of immune medicines enabled from its DECODE discovery platform.  The company’s first product in the clinic is a novel multiclonal T cell therapy consisting of T cells derived from the peripheral blood, activated against a curated set of antigens, and armed with a proprietary cytokine.  Repertoire is in clinical-stage immuno-oncology development today, targeting metastatic solid tumors.  In the field of autoimmunity, Repertoire is currently using its proprietary platform to discover novel epitopes and TCRs from patients with type 1 diabetes.  The company is also using its DECODE platform to discover infectious disease antigens and responding T cell clones.

Role Overview

As a key member of the lab operations and facilities team at Repertoire Immune Medicines, you will provide leadership, oversight, and management of our R&D laboratory environments.  Ideally, you have strong managerial and interpersonal skills, you are experienced in lab planning, asset management, and vendor management.  Additionally, you are a highly organized individual with strong attention to detail and a solid understanding of the activities, processes, and policies necessary for safe, efficient, and compliant laboratory operations across the company.

Key Responsibilities

  • Serve as primary of contact for all facilities related issues in our laboratory spaces, acting as liaison to leadership, property management, contractors, and personnel.
  • Supervise and mentor other lab operations team members as well as contract employees.
  • Work with R&D leaders to organize and manage current and future state of the company’s lab space and resources including logistics of laboratory equipment.
  • Write and oversee lab safety protocols and communicate and enforce laboratory safety rules. Be proactive to maintain an efficient and safe working lab environment.
  • Continually identify, improve, and implement new processes that increase the operational efficiency of the facility and lab operations.
  • Lead and be a part of 24-hour response team for facility and EH&S issues and emergencies.
  • Responsible for laboratory equipment procurement and maintenance including negotiations, establishing, and managing service contracts, tracking, and coordinating maintenance and calibrations, scheduling repairs, and maintaining a laboratory equipment matrix.
  • Develop and maintain vendor relationships in support of the laboratory operations including those supporting the facility, providing equipment, and suppling reagents.
  • Oversee day-to-day management, coordination, training and ensuring scalability of Repertoire’s EH&S program.
  • Manage and track biohazardous and chemical waste.
  • Oversee technical aspects of laboratory operations including glass wash, autoclave workflows, chemical and biological inventory ordering and tracking systems, receiving and efficient dispersion of incoming materials, etc.
  • Operational oversight of incoming and outgoing shipments.


  • Bachelor’s degree in a scientific discipline or equivalent work experience.
  • At least 6-8 years’ experience working in lab operations or facility management roles with 2-4+ years in a role that includes staff oversight, preferably in biotech.
  • Strong collaborator who thrives on working with multiple stakeholders in a matrixed environment and possesses the ability to adjust accordingly to accommodate changing priorities.
  • Demonstrated ability to effectively manage multiple projects, operate under pressure, and consistently meet deadlines
  • Exceptional organizational and communication skills, both verbal and written.
  • Demonstrated experience in overseeing initiatives and/or resources dedicated to laboratory safety and associated regulatory guidelines.
  • Someone who thrives on making a difference and displays a high degree of maturity, honesty, trust, and integrity.
  • Previous post-graduate laboratory experience highly desired.
  • Ability to perform the physical demands of the role including lifting moderately heavy boxes, prolonged standing, pushing gas tanks, etc.
  • Experience with HVAC, electrical, janitorial, and other facility related duties highly desired.


Repertoire is committed towards social responsibility and developing an inclusive culture.  Much as the power of the immune system lies in the diversity of T and B cells, we believe that our work requires the creativity and ingenuity of a diverse workforce, and we are committed to pursuing that in all facets of the work experience at Repertoire.  We will continue to educate ourselves about the inequities and barriers present in our society and act as a company where we can make a difference.

Repertoire is proud to be an Equal Opportunity Employer.