Program Manager, Research & Development

Research & Development Cambridge, Massachusetts


Company Overview

Repertoire Immune Medicines is a clinical-stage biotechnology company working to unlock and direct the remarkable power of the human immune system to prevent or treat cancer, as well as autoimmune and infectious disease.  The company is founded on the belief that the repertoire of T cell receptor (TCR)-antigen codes that drive health and disease represents one of the greatest opportunities for innovation in medical science.  Repertoire scientists created and developed the DECODE and DEPLOY suite of technologies, which allow in-depth characterization of TCR-antigen pairs, and the ability to rationally design and develop novel targeted immune medicines.

From its sites in Cambridge, Mass., and Zurich, Switzerland, Repertoire’s team of more than 120 is creating a new category of immune medicines enabled from its DECODE discovery platform.  The company’s first product in the clinic is a novel multiclonal T cell therapy consisting of T cells derived from the peripheral blood, activated against a curated set of antigens, and armed with a proprietary cytokine.  Repertoire is in clinical-stage immuno-oncology development today, targeting metastatic solid tumors.  In the field of autoimmunity, Repertoire is currently using its proprietary platform to discover novel epitopes and TCRs from patients with type 1 diabetes.  The company is also using its DECODE platform to discover infectious disease antigens and responding T cell clones.

Role Overview

This role is part of research and development operations group at Repertoire Immune Medicine.  We harness and deploy the intrinsic ability of T cells to prevent and cure disease.  Our research and development scientists created and developed a suite of technologies for its DECODE discovery and DEPLOY product platforms that allow in-depth characterization of the immune synapse and the ability to rationally design and clinically develop multi-clonal immune medicines.

You will provide program management support to research and clinical stage drug development programs and work alongside scientific program team leads to deliver on project/program plans, budget, and overall support ensuring alignment across functions and programs.  The Program Manager plays a critical role in facilitating the use of processes and tools, risk assessment and mitigation, strategic plans, resource plans, cross-functional plans, and timelines across their programs.

Key Responsibilities

  • Support and work alongside the scientific project/program leads to drive programs to successful outcomes.
  • Facilitate program team meetings including meeting agendas, minutes, action items, and decisions.
  • Proactively identify and communicate critical path items to PTLs and teams.
  • Ensure functional activities are carried out according to timelines and within budgeted costs/resources.
  • Develop project/program plans and timelines; manage the execution of program plans; track and manage milestones within the defined scope, time, and cost constraints; support coordination and communication between teams.
  • Facilitate team preparation for data-driven recommendations for key decisions enabling endorsement by stakeholders.
  • Proactively identify program issues including those related to timing, resources, and funding to prevent delays in program milestones.  Responsible for taking active role in issue resolution and risk mitigation plans.
  • Support program partnerships and alliances as well as business development activities, as needed.
  • Support overall program management function by contributing to establishment of project/program standards, templates, and processes.


  • Bachelor of Science degree (Biology, Molecular Biology, Microbiology preferred).
  • Minimum 3 years experience in pharmaceutical/biotechnology industry. Experience in project/program management a plus.
  • Experience managing the financial aspects of project/program management including planning, negotiating, budgeting, and reporting.
  • Proficiency with common software and project management tools, practices, and methodology, including MS Project, SmartSheet, and SharePoint.
  • Ability to effectively plan, prioritize, and coordinate multiple tasks and adjust to changing priorities to deliver results to tight deadlines.
  • Ability to think critically, interpret regulations, and/or standards apply them to changes and determine resulting course of actions.
  • Strong influencing skills including negotiation, meetings management, and group dynamics, ability to balance concerns of line management with objectives of cross functional teams.
  • Good understanding of research, development, and drug-development processes.
  • Ability to rationalize both strategically and tactically and be able to present recommendations to senior leaders and key stakeholders.
  • Dynamic, independent, flexible, well-organized, pro-active, collaborative-minded individual interested in contributing to excellent research science in an entrepreneurial environment.


Repertoire is committed towards social responsibility and developing an inclusive culture.  Much as the power of the immune system lies in the diversity of T and B cells, we believe that our work requires the creativity and ingenuity of a diverse workforce, and we are committed to pursuing that in all facets of the work experience at Repertoire.  We will continue to educate ourselves about the inequities and barriers present in our society and act as a company where we can make a difference.

Repertoire is proud to be an Equal Opportunity Employer.