Director of Precision Based Medicine

Research & Development San Diego, California


We’re a different kind of biotech company.  And we’re here to make a difference.

Prometheus Biosciences, Inc. (Nasdaq: RXDX), is a clinical-stage biotechnology company pioneering a precision medicine approach for the discovery, development, and commercialization of novel therapeutic and companion diagnostic products for the treatment of immune-mediated diseases, starting first with inflammatory bowel disease (IBD).

The Company’s precision medicine platform, Prometheus360™, combines proprietary bioinformatics discovery methods with one of the world’s largest gastrointestinal bioinformatics databases to identify novel therapeutic targets and develop therapeutic candidates to engage those targets. Prometheus is headquartered in San Diego, CA.


  • Coordinate research and development efforts between the discovery, data science, biomarker, and nonclinical development groups with a focus on precision therapeutics strategy
  • Work with internal teams and collaborators on target identification and prioritization for new programs
  • Advise on analytical assays for the development of our therapeutic programs
  • Provide immunology expertise during diligence and play a key role in licensing decisions


  • PhD, MS, or other relevant post-graduate degree in Immunology or related field with at least 10 years of experience in academia and/or industry, preferably in the field of auto-immune diseases.
  • Familiar with the integration of bioinformatics and high throughput approaches into target discovery and validation workflows; familiar with current data science methods and lexicon.
  • Prior experience with biomarkers and precision drug development is desirable.
  • Self-motivated with excellent planning, problem-solving, organizational and communication skills. Enjoys training other with an excellent track record of supervising more junior team members.
  • Strong communicator and presenter, with the ability to persuade others and foster open communication across internal and external groups
  • Solid project management skills with ability to manage multiple complex projects in a cross-functional environment with good understanding of project management process.
  • Strong ability to influence outcomes without direct authority and ability to hold oneself and others
  • accountable for commitments.
  • Ability to create and deliver effective presentations to working teams and senior management



  • A hands-on, entrepreneurial style with a sense of urgency, a bias toward action, comfort with calculated risk, and the ability to analyze situations rapidly and make prudent decisions
  • The ability to crystallize and convey an audacious, holistic vision and impact story to stakeholders at all levels with passion and presence
  • The requisite scientific acumen and communication skills to influence and collaborate with key scientific, regulatory, and business leaders
  • Sound strategic, clinical, technical, operational, and ethical judgment with uncompromising integrity
  • All qualified applicants are considered for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity, national origin, disability, veteran status or other protected class.