Scientist/Senior Scientist, Analytical Chemistry

Analytical Chemistry Cambridge, Massachusetts


Scientist/Senior Scientist, Analytical Chemistry

What’s in it for you?

In this role, you’ll have an opportunity to support the advancement of Mersana’s Antibodies and ADCs within our Analytical R&D organization. Since we are on the cutting edge of a new therapeutic category with its own unique testing requirements, we will take your existing expertise in method development, validation/qualification and transfer, and complement it with our advanced knowledge of antibody, polymer, small molecule, and ADC chemistry. You’ll also have an opportunity to form close partnerships with CMOs, CROs, and internal stakeholders. If you are passionate about science and enjoy being creative and not afraid to be challenged, this is a great opportunity to have an impact on Mersana’s novel platform technology and 1st in-class ADC development. We will work as a team to expand our knowledge base of our proprietary ADCs in order to enable their evolution towards optimized cancer therapies. You will be immersed in a learning organization, with a need to bring an open mind and an interest in mastering this new therapeutic space at a rapid pace.


How do you know if you’re the right fit?

You will have significant experience in:

  • Protein analytical chemistry, peptide mapping, protein post-translational modifications, higher order structural analysis using chromatographic and mass spectroscopic techniques.
  • Various analytical techniques, such as chromatographic separations (reverse phase, size exclusion, hydrophilic interaction, hydrophobic interaction, ion exchange) and capillary electrophoretic techniques.
  • Designing and performing method development independently


The other stuff

This is typically a role best suited for PhD, or MS candidates in Analytical Chemistry, Biochemistry, Biophysics, or related fields with 0-5 years of industrial experiences in LC-MS, with:

  • Hands on experience with monoclonal antibody, fusion protein, and bispecific antibody analysis is desirable.
  • Ability to interpret results, present data, and write reports.
  • Demonstrated troubleshooting and problem-solving capability.
  • Proficiency with standard computer applications, including advanced software for LC and MS data analysis.
  • Hands on experience with UPLC, Thermo QE, SCIEX QTrap, Bruker Compact Q-TOF, and PMI software is a plus.
  • Knowledge of regulatory requirements is a plus.
  • Excellent communication and interpersonal skills working in a highly interactive matrix team.
  • Being energetic, highly self-motivated, and able to work effectively and collaboratively in fast-paced teams.


Position is eligible for bonus, option awards and benefits including medical, dental and life insurance, 401(k) participation, vacation, and paid holidays.

Successful candidate must be authorized to work in the United States.

Mersana Therapeutics, Inc. is an equal opportunity employer.