Director, Immunology

Research & Development Cambridge, Massachusetts


Description

We are seeking a Director, Immunology (Platforms) to provide leadership to a team of scientist in discovery of disease relevant antigens and TCRs.  

You will lead teams in development, standardization, automatization and deployment of techniques and assays to decode immune responses in health and disease.

This is a key position for Repertoire’s decoding efforts and you will work closely with heads of Platform Technology and Computational Biology Teams to teams to establish state-of-the-are immune decoding capabilities

Key Rsponsibilities:

  • Lead the Platform Immunology team and be responsible for program related, scientific and operational objectives.
  • Establish, optimize and qualify Repertoire proprietary approaches for decoding of the immune synapse
  • Develop and qualify other assays that complement Repertoire’s platforms in thorough understanding of immune response in patients taking part in observational or interventional clinical studies.

 What you will bring to the role:

Ph.D. in Immunology or similar field with minimum of 10 years of working experience in academia or industry.

In depth knowledge of T cell immunology, including laboratory techniques related to assessment of T cell function and specificity

Experience working with recombinant TCR systems

Experience with multi-color flow cytometry for T cell characterization.

Experience with T cell-based assays such as MHC/peptide tetramer, ELISpot, Luminex, cytotoxicity, and TCR sequencing.

Experienced in running analytical testing on patient samples, including on clinical trial samples

 Desirable skills

  • Excellent communication skills and ability to work in a fast-paced environment and adapt to evolving priorities
  • Ability to lead several teams, both scientifically and strategically, managing in-line and matrixed teams
  • Proven track record of building effective relationships, demonstrate energy and accountability
  • Ability to work in a fast-paced and quickly changing environment