PACT Pharma Careers

Description

PACT Pharma is an exciting, well-funded clinical-stage company developing personalized adoptive T cell therapies for the eradication of solid tumors. Our private designer T cells are created by analyzing a patient’s individual tumor and engineering T cells to kill that specific tumor. 

If you desire a stimulating fast-paced environment, working with intelligent people who are making an impact in cancer, you will want to join the PACT Pharma team.  We are a rapidly expanding, innovative, and collaborative workforce working towards one main goal, eradicating cancer! 

We are in the San Francisco bay area, the heart of the world’s premier biotechnology research hub. PACT Pharma offers a competitive compensation and benefits package, including participation in the aggressive growth of the company in the form of stock option grants. 

We are currently recruiting for a Production Specialist who will report to the Manufacturing Supervisor and continue advancing PACT’s cutting edge engineered cell product. This will be a unique opportunity to see your ideas rapidly translate into the clinic and impact patient lives. 

Responsibilities:

Under the supervision of the Supervisor/ Manager, the Production Specialist will have the opportunity to participate in both manufacturing processes of immunotherapy cell products within a GMP environment, with the main focus in Plasmid Manufacturing. The duties of this position will primarily consist of manufacturing plasmids including activities such as bacterial culture management, and downstream purification (Ion Exchange Chromatography, Hydrophobic Interaction Chromatography, Tangential Flow Filtration).  Furthermore, you will be responsible for completing successful qualifications and ongoing support procedures for cleanroom operations and assisting in the development, writing, and review of SOPs, material specifications, standard manufacturing procedures, batch records, and other GMP documentation. The ideal candidate must have a collaborative and inquisitive nature, must possess excellent organizational and verbal and written communication skills, and be flexible in their working hours.  

• Perform required processing and manipulations required to produce and assess safe and efficacious products
• Proficiently functions within ISO cleanroom environments, ensuring personal and product safety
• Operate with the proper aseptic technique when handling all product and materials
• Consistently produce a high level of documentation accuracy and clarity
• Perform programmed microbial operations using specific equipment and closed systems
• Proficiently operate and maintain equipment according to designed procedures
• Manipulate products according to established standard operating procedures and batch records
• Participating in clinical trial support and studies may include but are not limited to sample preparation, sample shipping, media, and reagent preparation.
• Conduct and complete investigations for deviations in a timely manner 

Qualifications:

• Bachelor’s degree or associate degree in a biologics, biotechnology, or related field preferred
• A minimum of 2 years of applicable experience in the life science industry or cGMP manufacturing
• Experience working with bioreactors or fermentation operation preferred
• Experience working with chromatography and filtration operation preferred
• Aseptic processing and clean room experience required
• Strong work ethic, methodical approach to new challenges
• Must be able to work as a team, as well as independently with minimal supervision
• Demonstrates tact and courtesy in dealing with others
• Excellent organizational skills and attention to detail
• Good verbal and written communication skills
• Skills in Microsoft Office (Excel, Word) preferred
• Able to adapt to company growth and evolving responsibilities
• Ability to work a flexible schedule that may include nights, weekends, and/or holidays

Physical Demands:

The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of the job. While performing the duties of this job, the employee is frequently required to stand; walk; sit; bend; stretch; use hands to finger, handle or feel; reach with hands and arms; and talk or hear. The employee is regularly required to climb or balance; stoop, kneel, or crouch. The employee is frequently required to lift and/or move up to 30 pounds. Non-absorbent laboratory coats are required, as well as latex (or a non-latex substitute) gloves. When working with potentially hazardous materials that may spray, aerosol, or otherwise contact skin or mucous membranes, face shields or goggles must be worn. Heavy cryo gloves must be used when working with liquid nitrogen.  

PACT Pharma is proud to be an equal opportunity employer and strives to build a diverse and inclusive team. We do not discriminate on the basis of race, color, national origin, religion, gender, sexual orientation, age, marital status, veteran status, or disability status.