Description

Who We Are

BioMarin is a leading rare disease biotechnology company focused on genetically defined conditions.

Guided by our purpose to develop medicines that make a profound impact on people’s lives, our global teams have delivered a portfolio of therapies since our founding in 1997. Our revolutionary treatments for conditions like achondroplasia (the most common form of dwarfism), PKU (phenylketonuria), CLN2, a form of Batten disease, and a number of forms of MPS (mucopolysaccharidosis) offer new possibilities for patients and families who previously had few, if any, available options. More recently, with the close of the Amicus acquisition, our portfolio has expanded to include therapies for Fabry disease and Pompe disease, expanding our ability to reach more people living with rare genetic conditions.

Our success comes from our unwavering commitment to excellence, our deep understanding of patient needs, our scientific expertise, and our world-class manufacturing capabilities. At the heart of BioMarin is a dedicated team of the brightest minds in the industry working together to deliver innovative therapies to patients and families around the world.

About Worldwide Research and Development

From research and discovery to post-market clinical development, our R&D engine involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class and best-in-class therapeutics that provide meaningful advances to patients who live with rare diseases.

Job Title: Research Associate 2

Work Type: Contract

Job Summary:

Perform & document scientific experiments in collaboration with cross-functional stakeholders as part of the BCoE or Site strategy, and/or in support of BioMarin’s commercial & clinical product portfolio.

Responsibilities:

List the major responsibilities of the job.

Laboratory /Project work:

• Executes defined procedures independently to support BCoE studies and investigation activities with lab scale upstream processes in the multi-product lab.
• In addition to quick learning of core scientific techniques, principles and protocols, owns small project portions reliable execution and able to summarizes findings.
• Understanding the principles of aseptic operation and experience in working in biosafety cabinets.
• Experience in daily mammalian cell culture activities, including cell thawing and cell banking, seed train expansion etc.
• Experience in bioprocessing, including bioreactor inoculation, daily monitoring, sampling and in-process analysis utilizing standard bioprocess analytical equipment.
• Understanding of perfusion bioprocess is desirable.
• Experience in depth filtration and ultrafiltration is desirable.
• Produces accurate, reproducible data entries and maintains laboratory quality through adherence to safety and SOPs and able to troubleshoot common problems with guidance.
• Expands technical toolkit by adapting and troubleshooting process steps or assays, applies appropriate methods and interprets basic data trends.
• Updates and refines SOP/BPD documentation.
• Assists in drafting concise technical summaries.
• Understanding of microbial cell expansion and fermentation process execution is desirable.
• Understanding of downstream purification process is desirable.

General:

• Execute and complete projects independently.
• Generate and review data, makes data analysis.
• Maintain up-to-date documentation of laboratory work carried out including documentation storage and archiving in accordance with GLP.
• Support updates of lab instructions, BPDs, SOPs, templates.
• Support maintenance and calibration of lab equipment with accompanying documentation.
• Contribute to the evaluation of new equipment.
• Be a team player with excellent communication skills.
• Play an active role in maintaining and enhancing the safety of the workplace and the laboratories.
• Comply with applicable GxP regulations, SOPs, HSE, & other guidelines in the laboratory as applicable.
• May be required to work periodically out of normal business hours.

Scope:

• Quantify the scope or impact of the job in terms of revenue, expenses, capital investment, headcount, etc

Key Performance Metrics:

• Adherence to project plans & deliverables
• Adherence to applicable GxP and EHS requirements
• Technical reports executed on time and on quality
• Efficient technical exchange with Project leads

Education:

• State both the minimum and the preferred educational attainment (or equivalent experience), and describe essential and desired subject matter, certifications, special training, etc.
• Bachelor’s degree or higher in Science or Engineering

Experience:

• State both the minimum and the preferred number of years of relevant experience, and describe the essential functions of the job
• A minimum of 1 year experience in the pharmaceutical industry or equivalent strong laboratory experience.
• Working knowledge of pharmaceutical regulatory requirements appropriate to level and understanding of the cGMP manufacturing process for Biologics.

Note: This description is not intended to be all-inclusive, or a limitation of the duties of the position. It is intended to describe the general nature of the job that may include other duties as assumed or assigned.

Equal Opportunity Employer/Veterans/Disabled

An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

Ireland Safety Responsibility
Support the organisation’s commitment to environmental protection, injury prevention, and continual improvement of EHS management systems. Actively contribute to a safe and environmentally responsible workplace by identifying hazards, reporting incidents and participating in EHS initiatives and training.