Director, Health Economics & Outcomes Research, Hemophilia

Location:  London, United Kingdom Category: Commercial Operations



BioMarin is the world leader in delivering therapeutics that provide meaningful advances to patients who live with serious and life-threatening rare genetic diseases. We target diseases that lack effective therapies and affect relatively small numbers of patients, many of whom are children. These conditions are often inherited, difficult to diagnose, progressively debilitating and have few, if any, treatment options. BioMarin will continue to focus on advancing therapies that are the first or best of their kind.


BioMarin’s Commercial organization supports our global sales and marketing efforts around the world. Our global sales force continues to solidify the company’s commercial presence in the United States and Europe and is rapidly growing in other regions, such as Latin America, the Middle East and Asia-Pacific. Come join our team and make a meaningful impact on patients’ lives.





This role will focus on developing the value argumentation and payer evidence strategy and execution for BioMarins marketed and pipeline programs, specifically BioMarins investigational haemophilia gene therapy valoctocogene roxaparvovec (BMN 270).  Key activities include:

         Lead development of the BMN 270 global payer evidence strategy

         Lead HEOR global and EMEA evidence generation, synthesis and dissemination in collaboration with other functions including Medical Affairs and Biometrics.

         Support the reimbursement processes in the EMEA region including support for the development of reimbursement dossiers and the adaption of economic models.




  • Plan, develop, synthesize and disseminate HEOR evidence to demonstrate the value of BMN 270
  • Coordinate the BMN 270 Global Value and Access Team
  • Represent market access in global cross-functional forums including the Data and Evidence Team and the Core Development Team
  • Communicate market access perspective in clinical and observational study programs
  • Support EMEA reimbursement submissions with HEOR requirements
  • Continue innovation in approaches for HEOR in rare diseases




The scope of the role will part of the global HEOR Centre of Excellence and will comprise of planning and leading global HEOR evidence generation within the haemophilia franchise as well as providing support and expertise to the regional and local market access teams as required.




  • Bachelor’s degree in relevant field (e.g. pharmacy, medical science, science)
  • Post graduate qualifications (Masters or PhD) in public health, health economics, epidemiology or statistics preferred




  • Minimum 8-10 years of HEOR experience obtained from either a consulting or pharmaceutical industry background
  • Sound knowledge and experience of different payer architypes and appreciation for the broader market access environment ideally gained across multiple countries
  • Haemophilia experience is preferred




No responsibility for supervision.




Liaising with internal market access, commercial, medical, clinical and regulatory departments and externally with the key decision makers, health economists, clinical experts and patient organisations.




  • Excellent verbal and written communication, collaboration, influence, strategic, analytical and problem-solving skills are required
  • Demonstrated ability to manage a range of HEOR evidence projects including cost-effectiveness models, budget impact models, systematic literature reviews and real world data analysis
  • Ability to provide input into clinical program through input into trial designs, statistical analysis plans and study reports
  • Demonstrated ability to gain alignment of stakeholders including internally Commercial, Medical, Clinical and Regulatory departments and externally key decision makers, health economists, clinical experts and patient organizations
  • Working knowledge of common statistical packages and reference management software would be an advantage.



Note:  This description is not intended to be all-inclusive or a limitation of the duties of the position.  It is intended to describe the general nature of the job that may include other duties as assumed or assigned.