Senior Research Associate, Immunohistochemistry/Translational Science
Description
Senior Research Associate, Immunohistochemistry/Translational Science
About us:
Arcus Biosciences is an exciting growth company founded on the vision of creating best-in-class cancer therapies. We are an oncology-focused biopharmaceutical company leveraging deep cross-discipline expertise to discover highly differentiated oncology therapies for patients with significant unmet medical needs.
Job Summary:
We have an opening for a Senior Research Associate (SRA) in the Translational Sciences group with expertise in histology and immunohistochemistry (IHC) to support biomarker discovery. The candidate will be responsible for performing IHC/IF assay development and analysis. The ideal candidate should have experience with many elements of tissue-based research, including tissue processing, embedding, microtomy/cryotomy (sectioning), routine IHC and histology stains, microscopy/imaging, and digital image analysis. The role will also entail maintaining histology laboratory equipment and an inventory/ordering of critical materials and reagents used for IHC applications. Candidates with a strong interest in histology, oncology, and pathology, who desire to build expertise in this field are encouraged to apply. The successful applicant will have a proactive and collaborative work style, a positive attitude, outstanding attention to detail, organization skills, and an interest in translational science and tissue diagnostics. Successful applicants will have strong communication/presentation skills, work ethics, and can work in a highly collaborative, fast-paced environment.
Job Responsibilities:
The job duties and responsibilities for this position include, but are not limited to:
- Develop and validate novel IHC assays to support our clinical and preclinical programs.
- Collaborate with preclinical research teams to build assays with clinical applications in mind
- Imaging and analyzing single chromogenic IHC stains as well as multiplex immunofluorescent stains using both standard scoring methods and digital image analysis software
- Tissue procurement and generation of cell pellet controls to support assay development needs
- Presenting data regularly at project team meetings and communicating effectively across different functional teams within our organization (pharmacodynamics, biomarker ops, biology, etc)
- Procurement of the tissues and reagent ordering for the efficient day-to-day running of the lab
Qualifications:
- BS or MS or equivalent degree with ≥4 years of experience, including substantial time in a fast-paced industrial environment, with an immunohistochemistry background appropriate for this position. The title will be commensurate with experience.
- Solid working knowledge and hands-on experience with IHC techniques, including different automated staining platforms, whole slide scanning, and a software suite for image analysis.
- Experience with tissue processing, embedding, and sectioning is required
- Experience in assay development and validation of tissue-based biomarker assays, including technical oversight of vendor assay transfer and validation a plus.
- Cell culture experience is required
- Onsite lab-based position
This is a lab-based position based at our Hayward, CA location. The anticipated salary range for fully qualified candidates applying for this position is $95,000 - $130,000. Factors such as relevant experience, education, duration of experience, and length of industry experience will influence the actual title and salary offered. In addition to a competitive market-based salary, Arcus offers the opportunity to participate in stock programs, a performance-based bonus, and a comprehensive benefits package. Additional information about our total rewards program can be found here: https://arcusbio.com/careers/.
Arcus Biosciences is an Equal Opportunity Employer and prohibits discrimination and harassment of any kind. Arcus is committed to the principle of equal employment opportunity for all employees and does not discriminate based on race, religion, color, sex, gender identify, sexual orientation, age, non-disqualifying physical or mental disability, national origin, veteran status, or any other legally protected status. EOE/AA/Vets.
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